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SEMA4A Antibody

ArtNr PRS-58-716-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Schmidt-Kastner, R., et al. Mol. Vis. 14, 125-135 (2008) :
Toyofuku, T., et al. EMBO J. 26(5):1373-1384(2007)
Abid, A., et al. J. Med. Genet. 43(4):378-381(2006)
NCBI SEMA4A
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Semaphorin-4A, Semaphorin-B, Sema B, SEMA4A, SEMAB, SEMB
Lieferbar
Manufacturer - Applications
For WB starting dilution is: 1:500
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
blue ice or room temperature
Storage Conditions
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
84 kDa
Manufacturer - Research Area
Neuroscience
Background
This gene encodes a member of the semaphorin family ofsoluble and transmembrane proteins. Semaphorins are involved innumerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is asingle-pass type I membrane protein containing animmunoglobulin-like C2-type domain, a PSI domain and a sema domain.It inhibits axonal extension by providing local signals to specifyterritories inaccessible for growing axons. It is an activator ofT-cell-mediated immunity and suppresses vascular endothelial growthfactor (VEGF)-mediated endothelial cell migration and proliferationin vitro and angiogenesis in vivo. Mutations in this gene areassociated with retinal degenerative diseases including retinitispigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10).Multiple alternatively spliced transcript variants encodingdifferent isoforms have been identified.
Protein Gi #
29840871
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen
This SEMA4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human SEMA4A.
Clonality
Polyclonal
NCBI Official Name
Semaphorin-4A
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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