ZIP10 Antibody

ArtNr	PRS-6099-0.02mg
Hersteller	ProSci
Menge	0.02 mg
Quantity options	0.02 mg 0.1 mg
Kategorie	Oncology Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Breast Cancer Thyroid Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Kaler P and Prasad R. Molecular cloning and functional characterization of novel transporter rZip10 (Slc39a10) involved in zinc uptake across renal brush-border membrane. Am. J. Renal Physiol.2007; 292:F217-29. Taylor KM and Nicohlson RI. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim. Biophys. Acta.2003; 1611:16-30. Pawan K, Neeraj S, Sandeep K, et al. Upregulation of Slc39a10 gene expression in response to thyroid hormones in intestine and kidney. Biochim. Biophys. Acta.2007; 1769:117-23. Kagara N, Tanaka N, Noguchi S, et al. Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells. Cancer Sci.2007; 98:692-7.
NCBI	Slc39a10
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ZIP10 Antibody:
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	+4C storage
Manufacturer - Research Area	Cancer, Cell Cycle
Background	ZIP10 Antibody: ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies.
By Type	Cancer, Cell Cycle
Badges	Trial Size
Modifications	None
Protein Gi #	149046180
Purification	ZIP10 Antibody is affinity chromatography purified via peptide column.
Positive Control 1	PRS-1306-0.1mg
Positive Control 2	PRS-10-901-4um
Concentration	1 mg/mL
Buffer	ZIP10 Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note	ZIP10 antibody can be used for detection of ZIP10 by Western blot at 1 - 2 μ g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ g/mL. For immunofluorescence start at 20 μ g/mL. Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Immunogen	ZIP10 antibody was raised against an 18 amino acid synthetic peptide near the center of human ZIP10. The immunogen is located within amino acids 550 - 600 of ZIP10.
Clonality	Polyclonal
NCBI Official Name	solute carrier family 39 (zinc transporter), member 10
NCBI Organism	Rattus norvegicus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.02 mg

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