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OGFOD2 Antibody

ArtNr PRS-6179-0.02mg
Hersteller ProSci
Menge 0.02 mg
Quantity options 0.02 mg 0.1 mg
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Citations Saito K, Adachi N, Koyama H et al. OGFOD1, a member of the 2-oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling. FEBS Lett. 2010; 584:3340-7.
Wehner KA, Schutz S and Sarnow P. OGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress. Mol. Cell. Biol. 2010; 30:2006-16.
Marina O, Hainz U, Biernacki MA, et al. Serologic markers of effective tumor immunity against chronic lymphocytic leukemia include nonmutated B-cell antigens. Cancer Res. 2010; 70:1344-55.
NCBI OGFOD2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias OGFOD2 Antibody: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
OGFOD2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Manufacturer - Research Area
Apoptosis
Background
OGFOD2 Antibody: OGFOD2 is a member of the 2-OG-Fe(II) dioxygenase family which plays an important role in ischemic survival and stress. Like the related protein OGFOD1, OGFOD2 is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. Little is known about the function of OGFOD2, but its similarity to OGFOD1 suggests that it is a novel stress granule component that may play an important proapoptotic role in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.
By Type
Apoptosis
Badges
Trial Size
Modifications
None
Protein Gi #
13375846
Purification
OGFOD2 Antibody is affinity chromatography purified via peptide column.
Positive Control 1
Concentration
1 mg/mL
Buffer
OGFOD2 Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note
OGFOD2 antibody can be used for detection of OGFOD2 by Western blot at 1 μ g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Manufacturer - Specificity
OGFOD2 antibody is predicted to not cross-react with other TPA1 protein family members. At least three isoforms are known to exist; this antibody will only detect the two larger isoforms.
Immunogen
OGFOD2 antibody was raised against a 17 amino acid synthetic peptide near the center of human OGFOD2.

The immunogen is located within amino acids 140 - 190 of OGFOD2.
Clonality
Polyclonal
NCBI Official Name
2-oxoglutarate and iron-dependent oxygenase domain containing 2
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.02 mg
Lieferbar: In stock
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