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ZIMP7 Antibody

ArtNr PRS-6235-0.02mg
Hersteller ProSci
Menge 0.02 mg
Quantity options 0.02 mg 0.1 mg
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Citations Huang CY, Beliakoff J, Li X, et al. hZimp7, a novel PIAS-like protein, enhances androgen receptor-mediated transcription and interacts with SWI/SNF-like BAF complexes. Mol. Endocrinol. 2005; 19:2915-29
Ueki N, Oda T, Kondo M, et al. Selection system for genes encoding nuclear-targeted proteins. Nat. Biotechnol. 1998; 16:1338-42.
Beliakoff J and Sun Z. Zimp7 and Zimp10, two novel PIAS-like proteins, function as androgen receptor coregulators. Nucl. Recept. Signal. 2006; 4:e017
Peng Y, Lee J, Zhu C, et al. A novel role for protein inhibitor of activated STAT (PIAS) proteins in modulating the activity of Zimp7, a novel PIAS-like protein, in androgen receptor-mediated transcription. J. Biol. Chem. 2010; 285:11465-75.
NCBI ZMIZ2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ZIMP7 Antibody: NET27,ZIMP7,hZIMP7,TRAFIP20,KIAA1886,HRIHFB2007,Zinc finger MIZ domain-containing protein 2,PIAS-like protein Zimp7
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
ZIMP7 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Manufacturer - Research Area
Signal Transduction
Background
ZIMP7 Antibody: ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
By Type
Signal Transduction
Badges
Trial Size
Modifications
None
Protein Gi #
54607108
Purification
ZIMP7 Antibody is affinity chromatography purified via peptide column.
Positive Control 1
Concentration
1 mg/mL
Buffer
ZIMP7 Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note
ZIMP7 antibody can be used for detection of ZIMP7 by Western blot at 0.25 - 0.5 μ g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Manufacturer - Specificity
At least four isoforms are known to exist. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members.
Immunogen
ZIMP7 antibody was raised against a 17 amino acid synthetic peptide near the center of human ZIMP7.

The immunogen is located within amino acids 270 - 320 of ZIMP7.
Clonality
Polyclonal
NCBI Official Name
zinc finger, MIZ-type containing 2
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.02 mg
Lieferbar: In stock
lieferbar

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