SLAMF4 Antibody

ArtNr	PRS-6253-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Quantity options	0.02 mg 0.1 mg
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Myeloma Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Breast Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Claus M, Meinke S, Bhat R, et al. Regulation of NK cell activity by 2B4, NTB-A and CRACC. Front. Biosci. 2008; 13:956-65. Sidorenko SP and Clark EA. The dual-function CD150 receptor sub-family: the viral attraction. Nat. Immunol. 4:19-24. Assarsson E, Kambayashi T, Persson CM, et al. 2B4/CD48-mediated regulation of lymphocyte activation and function. J. Immunol. 2005; 175:2045-9 Kim JR, Matther SO, Patel RK, et al. Altered expression of signalling lymphocyte activation molecule (SLAM) family receptors CS1 (CD319) and 2B4 (CD244) in patients with systemic lupus erythmatosus. Clin. Exp. Immunol. 2010; 160:348-58
NCBI	CD244
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	SLAMF4 Antibody: 2B4,NAIL,Nmrk,NKR2B4,SLAMF4,2B4,Natural killer cell receptor 2B4,NK cell activation-inducing ligand
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	SLAMF4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Manufacturer - Research Area	Immunology
Background	SLAMF4 Antibody: The signaling lymphocyte-activation molecule family member 4 (SLAMF4), also known as 2B4, is an important regulator of Natural Killer (NK) cell activation. It is expressed on NK cells as well as on subsets of T cells and interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in this autoimmune disease.
By Type	Immunology
Badges	Trial Size
Modifications	None
Protein Gi #	7706529
Purification	SLAMF4 Antibody is affinity chromatography purified via peptide column.
Positive Control 1	PRS-1224-0.1mg
Concentration	1 mg/mL
Buffer	SLAMF4 Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note	SLAMF4 antibody can be used for detection of SLAMF4 by Western blot at 1 - 2 μ g/mL. Antibody can also be used for immunofluorescence starting at 20 μ g/mL. For immunofluorescence start at 20 μ g/mL. Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Manufacturer - Specificity	At least three isoforms of SLAMF4 are known to exist. SLAMF4 antibody is predicted to not cross-react with other SLAM protein family members.
Immunogen	SLAMF4 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human SLAMF4. The immunogen is located within the last 50 amino acids of SLAMF4.
Clonality	Polyclonal
NCBI Official Name	CD244 molecule, natural killer cell receptor 2B4
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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