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PDGFRB Antibody

PDGFRB Antibody

Hersteller	ProSci
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Protein Aggregation, Clearance & Misfolding Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Astrocytoma By Organ Colorectal Cancer Heart & Blood Cancer Thyroid Cancer Calcium Binding Protein Markers Interneuron Markers
Typ	Antibody Polyclonal
Specific against	Human
Format	Liquid
Applikationen	WB, IF, IHC-P
Menge	400 ul
Host	Rabbit
ArtNr	PRS-63-122-400ul
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Shipping	blue ice or RT
By Research Area	Cancer, Signal Transduction
Immunogen	This PDGFRB antibody is generated from rabbits immunized with human recombinant PDGFRB protein.
Applications	For IHC-P starting dilution is: 1:10~50 For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50
Predicted Molecular Weight	124 kDa
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	PDGFRB
Accession #	P09619
Protein Gi #	129890
Ncbi Gene Id #	5159
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	PDGFRB
Ncbi Official Full Name	Platelet-derived growth factor receptor beta
Ncbi Organism	Homo sapiens
Swissprot #	P09619
Background	PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides.
Background References 1	Wu, H., et al., J. Biol. Chem. 278(42):40425-40428 (2003).
Background References 2	Whiteman, E.L., et al., Endocrinology 144(9):3811-3820 (2003).
Background References 3	Uren, A., et al., Oncogene 22(15):2334-2342 (2003).
Background References 4	Steer, E.J., et al., Acta Haematol. 107(2):113-122 (2002).
1st Image Caption	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PDGFRB antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
2nd Image Caption	Western blot analysis of anti-PDGFRB Pab in Y79 cell line lysates (35ug/lane).
3rd Image Caption	Confocal immunofluorescent analysis of PDGFRB Antibody with WiDr cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 06.06.2024

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