Vergleich

CDC14B Antibody

Hersteller ProSci
Kategorie
Typ Antibody Polyclonal
Specific against Human
Format Liquid
Applikationen WB, FC
Menge 400 ul
Host Rabbit
ArtNr PRS-63-773-400ul
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Shipping
blue ice or RT
By Research Area
Cell Cycle, Signal Transduction
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen
This CDC14B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 amino acids from the Central region of human CDC14B.
Applications
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Predicted Molecular Weight
57 kDa
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality
Polyclonal
Isotype
Rabbit Ig
Conjugate
Unconjugated
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration
batch dependent
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications
None
Ncbi Official Symbol
CDC14B
Accession #
O60729
Ncbi Gene Id #
8555
User Note
Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol
CDC14B
Ncbi Official Full Name
Dual specificity protein phosphatase CDC14B
Ncbi Organism
Homo sapiens
Swissprot #
O60729
Background
CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Background References 1
Bassermann, F., et.al., Cell 134 (2), 256-267 (2008)
Background References 2
Rosso, L., et.al., PLoS Biol.(6), E140 (2008)
1st Image Caption
Western blot analysis of CDC14B Antibody in 293 cell line lysates (35ug/lane)
2nd Image Caption
Flow cytometry analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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Lieferung vsl. bis 06.06.2024 

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