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CDC14B Antibody

CDC14B Antibody

Manufacturer	ProSci
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Adenocarcinoma Flow Cytometry Western Blot Primary Antibodies Astrocytoma By Organ Bladder Cancer Colorectal Cancer Thyroid Cancer Calcium Binding Protein Markers Interneuron Markers
Type	Antibody Polyclonal
Specific against	Human
Format	Liquid
Applications	WB, FC
Amount	400 ul
Host	Rabbit
Item no.	PRS-63-773-400ul
eClass 6.1	32160702
eClass 9.0	32160702
Available
Shipping	blue ice or RT
By Research Area	Cell Cycle, Signal Transduction
Homology	Predicted species reactivity based on immunogen sequence: Mouse
Immunogen	This CDC14B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 amino acids from the Central region of human CDC14B.
Applications	For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
Predicted Molecular Weight	57 kDa
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	CDC14B
Accession #	O60729
Ncbi Gene Id #	8555
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	CDC14B
Ncbi Official Full Name	Dual specificity protein phosphatase CDC14B
Ncbi Organism	Homo sapiens
Swissprot #	O60729
Background	CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Background References 1	Bassermann, F., et.al., Cell 134 (2), 256-267 (2008)
Background References 2	Rosso, L., et.al., PLoS Biol.(6), E140 (2008)
1st Image Caption	Western blot analysis of CDC14B Antibody in 293 cell line lysates (35ug/lane)
2nd Image Caption	Flow cytometry analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 7/4/2024