MLIP Antibody

Primary Antibodies

MLIP antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

MLIP Antibody: The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodies

Trial Size

154426278

PRS-1210-0.1mg

1 mg/mL

MLIP antibody can be used for detection of MLIP by Western blot at 1 μ g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ g/mL. For immunofluorescence start at 20 μ g/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

MLIP antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human MLIP.

The immunogen is located within the last 50 amino acids of MLIP.

muscular LMNA-interacting protein

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.