GRB10 Antibody

Primary Antibodies

GRB10 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

GRB10 Antibody: GRB10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules and function in diverse cellular processes. GRB10 is a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of GRB10 inhibits tyrosine kinase activity and results in growth suppression. GRB10 can also interact with the L isoform of the proapoptotic protein Bim. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts.

Trial Size

48762679

PRS-1220-0.1mg

GRB10 Antibody is supplied in PBS containing 0.02% sodium azide.

Predicted species reactivity based on immunogen sequence: Pig: (100%)

GRB10 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human GRB10.

The immunogen is located within amino acids 440 - 490 of GRB10.

growth factor receptor-bound protein 10

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.