NKX2-4 Antibody

ArtNr	PRS-6747-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Quantity options	0.02 mg 0.1 mg
Kategorie	Oncology Antibodies Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies By Organ Thyroid Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Wang CC, Brodnicki T, Copeland NG, et al. Conserved linkage of NK-2 homeobox gene pairs Nkx2-2/2-4 and Nkx2-1/2-9 in mammals. Mamm. Genome 2000; 11:466-8. Small EM, Vokes SA, Garriock RJ, et al. Developmental expression of the Xenopus Nkx2-1 and Nkx2-4 genes. Mech. Dev. 2000; 96:259-62. Hill JT, Chao CS, Anderson KR, et al. Nkx2.2 activates the ghrelin promoter in pancreatic islet cells. Mol. Endocrinol. 2010; 381-90.
NCBI	NKX2-4
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	NKX2-4 Antibody: NKX2D,NKX2.4,NKX2D,Homeobox protein NK-2 homolog D
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	NKX2-4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Manufacturer - Research Area	Stem Cell
Background	NKX2-4 Antibody: NKX2-4 (NK2 homeobox 4) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-4 is closely related to NKX2-1 and NKX2-4 and is specifically localized to the ventral diencephalon. Recent experiments in Xenopus have suggested that the homeodomain protein XANF is necessary for the activation of NKX2-4, but does not directly regulate its expression.
By Type	Stem Cell
Badges	Trial Size
Modifications	None
Protein Gi #	157426823
Purification	NKX2-4 Antibody is affinity chromatography purified via peptide column.
Positive Control 1	PRS-1288-0.1mg
Positive Control 2	PRS-17-208-1pack
Concentration	1 mg/mL
Buffer	NKX2-4 Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note	NKX2-4 antibody can be used for detection of NKX2-4 by Western blot at 1 μ g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ g/mL. For immunofluorescence start at 20 μ g/mL. Antibody validated: Western Blot in mouse samples; Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Homology	Predicted species reactivity based on immunogen sequence: Guinea pig: (100%), Rat: (86%), Chicken: (86%), Bovine: (71%)
Manufacturer - Specificity	NKX2-4 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-4 are known to exist; this antibody will detect both isoforms.
Immunogen	NKX2-4 antibody was raised against an 18 amino acid synthetic peptide near the center of human NKX2-4. The immunogen is located within amino acids 220 - 270 of NKX2-4.
Clonality	Polyclonal
NCBI Official Name	NK2 homeobox 4
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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