BCL3 Antibody

ArtNr	PRS-7183-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Quantity options	0.02 mg 0.1 mg
Kategorie	Oncology Antibodies Western Blot ELISA Primary Antibodies By Organ Skin Cancer Heart & Blood Cancer Lymphatic System Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Ohno H, Takimoto G, and McKeithan TW. The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control. Cell 1990; 60:991-7. Wulczyn FG, Naumann M, and Scheidereit C. Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B. Nature 1992; 358:597-9. Ibrahim HA, Amen F, Reid AG, et al. BCL3 rearrangement, amplification and expression in diffuse large B-cell lymphoma. Eur. J. Haematol. 2011; 87:480-5. Ge B, Li O, Wilder P, et al. NF-kappa B regulates BCL3 transcription in T lymphocytes through an intronic enhancer. J. Immunol. 2003; 171:4210-8.
NCBI	BCL3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BCL3 Antibody: BCL4, D19S37, BCL4, B-cell lymphoma 3 protein, Proto-oncogene BCL3, BCL-3
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Manufacturer - Applications	BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 μg/mL. Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Shipping Temperature	blue ice or room temperature
Storage Conditions	BCL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Molecular Weight	Predicted: 50 kDa
Manufacturer - Research Area	Cancer, Cell Cycle
Background	BCL3 Antibody: The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-κ -B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-κ -B proteins. The expression of this gene can be induced by NF-κ -B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-κ -B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.
Protein Gi #	164664508
Purification	BCL3 Antibody is affinity chromatography purified via peptide column.
Positive Control 1	PRS-1210-0.1mg
Concentration	1 mg/ml
Buffer	BCL3 Antibody is supplied in PBS containing 0.02% sodium azide.
Immunogen	Rabbit polyclonal BCL3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human BCL3. The immunogen is located within amino acids 360 - 410 of BCL3.
Clonality	Polyclonal
NCBI Official Name	B-cell CLL/lymphoma 3
NCBI Organism	homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Menge: 0.1 mg

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Lieferung vsl. bis 04.09.2025