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PRKCDBP Antibody

ArtNr PRS-7269-0.1mg
Hersteller ProSci
Menge 0.1 mg
Quantity options 0.02 mg 0.1 mg
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, ELISA, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Citations Briand N, Dugail I, and Le Lay S. Cavin proteins: New players in the caveolae field. Biochimie 2011; 93:71-7.
Izumi Y, Hirai S, Tamai Y, et al. A protein kinase Cdelta-binding protein SRBC whose expression is induced by serum starvation. J. Biol. Chem. 1997; 272:7381-9.
McMahon K, Zajicek H, Li W, et al. SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function. EMBO J. 2009; 28:1001-15.
Bai L, Deng X, Li Q, et al. Down-regulation of the cavin family proteins in breast cancer. J. Cell Biochem. 2012; 113:322-8.
NCBI PRKCDBP
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias PRKCDBP Antibody: SRBC, HSRBC, CAVIN3, cavin-3, SRBC, Protein kinase C delta-binding protein, Cavin-3, hSRBC
Lieferbar
Manufacturer - Applications
PRKCDBP antibody can be used for detection of PRKCDBP by Western blot at 1 - 2 μg/mL.

Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Shipping Temperature
blue ice or room temperature
Storage Conditions
PRKCDBP antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Molecular Weight
29 kDa
Manufacturer - Research Area
Cancer, Cell Cycle
Background
PRKCDBP Antibody: The protein kinase C delta (PKC-δ ) binding protein (PRKCDBP), also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.
Protein Gi #
47132587
Purification
PRKCDBP Antibody is affinity chromatography purified via peptide column.
Positive Control 1
Positive Control 2
Concentration
1 mg/ml
Buffer
PRKCDBP Antibody is supplied in PBS containing 0.02% sodium azide.
Homology
Predicted species reactivity based on immunogen sequence: Rat: (100%)
Immunogen
Rabbit polyclonal PRKCDBP antibody was raised against an 17 amino acid peptide near the center of human PRKCDBP.

The immunogen is located within amino acids 150 - 200 of PRKCDBP.
Clonality
Polyclonal
NCBI Official Name
protein kinase C, delta binding protei
NCBI Organism
homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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