MUC1 Antibody

Blue Ice

Predicted: 53 (+ multiple others) kDa
Observed:42, 120 kDa

Mucin 1 (MUC1) is membrane-bound protein member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces and also play a role in intracellular signaling (1). MUC1 is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. MUC1 is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas (1).

Trial Size

324120958

PRS-1201-0.1mg

MUC1 Antibody is supplied in PBS containing 0.02% sodium azide.

Predicted species reactivity based on immunogen sequence: Bovine: (83%)

MUC1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human MUC1.

The immunogen is located within the last 50 amino acids of MUC1 .

mucin 1, cell surface associated

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.