ArtNr |
PRS-76-798-0.05mg |
Hersteller |
ProSci
|
Menge |
0.05 mg |
Kategorie |
|
Typ |
Antibody Monoclonal |
Format |
liquid |
Applikationen |
FC |
Clon |
HMb1-1 |
Specific against |
Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Hamster - Armenian |
Isotype |
IgG |
Konjugat/Tag |
PE |
Citations |
Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. Kleinewietfeld, M., Starke, M., Di Mitri, D., Borsellino, G., Battistini, L., Rtzschke, O., Falk, K. (2009). CD49d provides access to untouched human Foxp3+ Treg free of contaminating effector cells.Blood,113(4), 827-836. Hemler, M. E. (1990). VLA proteins in the integrin family: structures, functions, and their role on leukocytes.Annual review of immunology,8(1), 365-400. |
NCBI |
Itgb1 |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
CD29, Fnrb, gpIIa, Gm9863, AA409975, AA960159, 4633401G24Rik, ENSMUSG00000051907, Itgb1 |
Lieferbar |
|
Manufacturer - Isotype |
Armenian Hamster IgG |
Shipping Temperature |
blue ice or room temperature |
Storage Conditions |
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. |
Manufacturer - Research Area |
Cancer |
Background |
The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDA molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain. It is expressed broadly on endothelial cells, epithelial, leukocytes, and smooth muscle. CD29 forms the VLA 1-6 complexes through the non-covalent interaction with the alpha integrins of CD49 a-f. The HMb1-1 antibody is capable of inhibiting T cell proliferation and blocking cell adhesion. |
Purification |
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product. |
Concentration |
Batch dependent |
Buffer |
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
Clonality |
Monoclonal |
NCBI Official Name |
integrin beta 1 (fibronectin receptor beta) |
NCBI Organism |
Mus musculus; Rattus norvegicus |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.