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CD29 Antibody [HMb1-1] (PE)

ArtNr PRS-76-798-0.05mg
Hersteller ProSci
Menge 0.05 mg
Kategorie
Typ Antibody Monoclonal
Format liquid
Applikationen FC
Clon HMb1-1
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Hamster - Armenian
Isotype IgG
Konjugat/Tag PE
Citations Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Kleinewietfeld, M., Starke, M., Di Mitri, D., Borsellino, G., Battistini, L., Rtzschke, O., Falk, K. (2009). CD49d provides access to untouched human Foxp3+ Treg free of contaminating effector cells.Blood,113(4), 827-836.
Hemler, M. E. (1990). VLA proteins in the integrin family: structures, functions, and their role on leukocytes.Annual review of immunology,8(1), 365-400.
NCBI Itgb1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias CD29, Fnrb, gpIIa, Gm9863, AA409975, AA960159, 4633401G24Rik, ENSMUSG00000051907, Itgb1
Lieferbar
Manufacturer - Isotype
Armenian Hamster IgG
Shipping Temperature
blue ice or room temperature
Storage Conditions
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area
Cancer
Background
The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDA molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain. It is expressed broadly on endothelial cells, epithelial, leukocytes, and smooth muscle. CD29 forms the VLA 1-6 complexes through the non-covalent interaction with the alpha integrins of CD49 a-f. The HMb1-1 antibody is capable of inhibiting T cell proliferation and blocking cell adhesion.
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality
Monoclonal
NCBI Official Name
integrin beta 1 (fibronectin receptor beta)
NCBI Organism
Mus musculus; Rattus norvegicus
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.05 mg
Lieferbar: In stock
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