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CD29 Antibody [HMb1-1] (PE)

CD29 Antibody [HMb1-1] (PE)

Item no.	PRS-76-798-0.05mg
Manufacturer	ProSci
Amount	0.05 mg
Category	Oncology Neuroscience Neural Adhesion Molecules Antibodies Flow Cytometry Primary Antibodies By Organ Skin Cancer
Type	Antibody Monoclonal
Format	liquid
Applications	FC
Clone	HMb1-1
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Hamster - Armenian
Isotype	IgG
Conjugate/Tag	PE
Citations	Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. Kleinewietfeld, M., Starke, M., Di Mitri, D., Borsellino, G., Battistini, L., Rtzschke, O., Falk, K. (2009). CD49d provides access to untouched human Foxp3+ Treg free of contaminating effector cells.Blood,113(4), 827-836. Hemler, M. E. (1990). VLA proteins in the integrin family: structures, functions, and their role on leukocytes.Annual review of immunology,8(1), 365-400.
NCBI	Itgb1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD29, Fnrb, gpIIa, Gm9863, AA409975, AA960159, 4633401G24Rik, ENSMUSG00000051907, Itgb1
Available
Manufacturer - Isotype	Armenian Hamster IgG
Shipping Temperature	blue ice or room temperature
Storage Conditions	The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area	Cancer
Background	The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDA molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain. It is expressed broadly on endothelial cells, epithelial, leukocytes, and smooth muscle. CD29 forms the VLA 1-6 complexes through the non-covalent interaction with the alpha integrins of CD49 a-f. The HMb1-1 antibody is capable of inhibiting T cell proliferation and blocking cell adhesion.
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	Batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality	Monoclonal
NCBI Official Name	integrin beta 1 (fibronectin receptor beta)
NCBI Organism	Mus musculus; Rattus norvegicus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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