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CD161 Antibody [HP-3G10] (PerCP-Cy5.5)

ArtNr PRS-76-839-25tests
Hersteller ProSci
Menge 25 tests
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen FC
Clon HP-3G10
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Konjugat/Tag PerCP, Cy5.5
Citations Mrquez, C., Trigueros, C., Franco, J. M., Ramiro, A. R., Carrasco, Y. R., Lpez-Botet, M., Toribio, M. L. (1998). Identification of a common developmental pathway for thymic natural killer cells and dendritic cells.Blood,91(8), 2760-2771.
Cosmi, L., De Palma, R., Santarlasci, V., Maggi, L., Capone, M., Frosali, F., ... Annunziato, F. (2008). Human interleukin 17producing cells originate from a CD161+ CD4+ T cell precursor.The Journal of experimental medicine,205(8), 1903-1916.
Exley, M., Porcelli, S., Furman, M., Garcia, J., Balk, S. (1998). CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Valpha 24Jalpha Q T cell receptor alpha chains.The Journal of experimental medicine,188(5), 867-876.
NCBI KLRB1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias NKR,CD161,CLEC5B,NKR-P1,NKRP1A,NKR-P1A,hNKR-P1A,KLRB1
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Mouse IgG1, kappa
Shipping Temperature
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area
Innate Immunity, Immunology
Background
The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A. CD161 is expressed on most natural killer cells, subsets of CD4+ and CD8+ T lymphocytes, gammadelta TCR T lymphocytes, a subset of CD3+ thymocytes, and especially on CD45RO+ T lymphocytes. Reports indicate that it may serve as a specific receptor for some natural killer cell targets and a possible stimulatory role.
By Type
Innate Immunity, Immunology
Modifications
None
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Manufacturer - Specificity
The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A.
Clonality
Monoclonal
NCBI Official Name
killer cell lectin-like receptor subfamily B, member 1
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 tests
Lieferbar: In stock
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