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ATF2 (Ab 62 or 44) Antibody

ATF2 (Ab 62 or 44) Antibody

Hersteller	ProSci
Kategorie	Oncology Neuroscience Aging & Neurological Disorders Neural Signaling Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies By Organ Bladder Cancer
Typ	Antibody Primary
Specific against	Human, Mouse, Rat
Format	Liquid
Applikationen	WB, IF, IHC
Menge	0.1 mg
Host	Rabbit
ArtNr	PRS-79-276-0.1mg
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Shipping	blue ice or RT
By Research Area	Other
Immunogen	ATF2 (Ab-62 or 44) antibody was raised against a peptide sequence around aa.serine 60~64 or 42~46 (N-D-S-V-I) derived from Human ATF2.
Applications	Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Specificity	This antibody detects endogenous level of total ATF-2 protein.
Predicted Molecular Weight	65 - 75 kDa
Purification	Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality	Polyclonal
Conjugate	Unconjugated
Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	1 mg/mL
Storage Conditions	Store antibody at -20˚ C for up to one year.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	ATF2
Accession #	NP_001871.2
Protein Gi #	22538422
Ncbi Gene Id #	1386
Ncbi Official Symbol	ATF2
Ncbi Official Full Name	activating transcription factor 2
Ncbi Organism	Homo sapiens
Swissprot #	P15336
Background	Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
Background References 1	Sevilla A, et al. (2004) J Biol Chem. 279 (26): 27458-27465. Sakurai A, et al. (1991) Biochem Biophys Res Commun. 181 (2): 629-635. Abdel-Hafiz H A, et al. (1992) Mol Endocrinol. 6: 2079-2089. Gupta S, et al. (1995) Science. 267: 389-393. Van Dam H, et al. (1995) EMBO J. 14 (8): 1798-1811.
1st Image Caption	Western blot analysis of lysed extracts from 293 and 3T3 cells using ATF2 (Ab-62 or 44).
2nd Image Caption	Top Image: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ATF2 (Ab-62 or 44).Bottom Image: Immunofluorescence staining of methanol-fixed HeLa cells using ATF2 (Ab-62 or 44).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.1 mg

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