Caspase 3 Antibody

ArtNr	PRS-79-641-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Kategorie	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies Cell Biology Cell Status Apoptosis Western Blot Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Gervais, F. G et al. Cell 97: 395-406, 1999. Nicholson, D. W. et al. (1995) Nature 376, 37-43.
NCBI	CASP3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CPP32,SCA-1,CPP32B,SCFR,Apopain
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store antibody at -20˚ C for up to one year.
Molecular Weight	35 19 17 kDa
Manufacturer - Research Area	Apoptosis, Cancer
Background	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
By Type	Apoptosis, Cancer
Modifications	None
Protein Gi #	14790119
Purification	Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration	1 mg/mL
Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Note	Western Blot: 1:1000
Manufacturer - Specificity	This antibody detects endogenous level of total Caspase 3 protein.
Immunogen	Caspase 3 antibody was raised against a peptide sequence around aa.29~33 (S-G-I-S-L) derived from Caspase 3.
Clonality	Polyclonal
NCBI Official Name	caspase 3, apoptosis-related cysteine peptidase
NCBI Organism	This antibody was raised against a peptide sequence around aa.29~33 (S-G-I-S-L) derived from Caspase 3.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.1 mg

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Lieferung vsl. bis 01.01.2026

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