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Caspase 3 Antibody

Caspase 3 Antibody

Item no.	PRS-79-641-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies Cell Biology Cell Status Apoptosis Western Blot Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Gervais, F. G et al. Cell 97: 395-406, 1999. Nicholson, D. W. et al. (1995) Nature 376, 37-43.
NCBI	CASP3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CPP32,SCA-1,CPP32B,SCFR,Apopain
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store antibody at -20˚ C for up to one year.
Molecular Weight	35 19 17 kDa
Manufacturer - Research Area	Apoptosis, Cancer
Background	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
By Type	Apoptosis, Cancer
Modifications	None
Protein Gi #	14790119
Purification	Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration	1 mg/mL
Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Note	Western Blot: 1:1000
Manufacturer - Specificity	This antibody detects endogenous level of total Caspase 3 protein.
Immunogen	Caspase 3 antibody was raised against a peptide sequence around aa.29~33 (S-G-I-S-L) derived from Caspase 3.
Clonality	Polyclonal
NCBI Official Name	caspase 3, apoptosis-related cysteine peptidase
NCBI Organism	This antibody was raised against a peptide sequence around aa.29~33 (S-G-I-S-L) derived from Caspase 3.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 1/1/2026

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