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TNFAIP1 Antibody

ArtNr PRS-8345-0.02mg
Hersteller ProSci
Menge 0.02 mg
Quantity options 0.02 mg 0.1 mg
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, ELISA, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Citations Liu M, Sun Z, Zhou A, et al. Functional characterization of the promoter region of human TNFAIP1 gene. Mol. Biol. Rep. 2010; 37:1699-705.
Hu X, Yan F, Wang F, et al. TNFAIP1 interacts with KCTD10 to promote the degradation of KCTD10 proteins and inhibit the transcriptional activities of NF-?B and AP-1. Mol. Biol. Rep. 2012; 39:9911-9.
Zhang CL, Wang C, Yan WJ, et al. Knockdown of TNFAIP1 inhibits growth and induces apoptosis in osteosarcoma cells through inhibition of the nuclear factor-?B pathway. Oncol. Rep. 2014; 32:1149-55.
Kim DM, Chung KS, Choi SJ, et al. RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells. Int. J. Cancer 2009; 125:2520-7.
NCBI TNFAIP1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Tumor necrosis factor,alpha-induced protein 1,BTB/POZ domain-containing protein TNFAIP1,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2,BACURD2,EDP1
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
TNFAIP1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Molecular Weight
Predicted: 35 kDa
Observed: 35 kDa
Manufacturer - Research Area
Apoptosis, Cancer, Innate Immunity
Background
TNFAIP1 is a BTB/POZ domain-containing protein that belongs to the KCTD10/BACURD family which mediates POZ-POZ interactions and chromatin modeling (1, 2). The expression of TNFAIP1 is developmentally regulated in a tissue-specific manner and can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells (3). TNFAIP1 may be involved in DNA repair, DNA synthesis, and cell apoptosis. TNFAIP1 is suggested to play a role in the process of cancer and in the innate immunity against the Hepatitis B virus (4, 5).
By Type
Apoptosis, Cancer, Innate Immunity
Badges
Trial Size
Modifications
None
Protein Gi #
10863937
Purification
TNFAIP1 Antibody is affinity chromatography purified via peptide column.
Positive Control 1
Concentration
1 mg/mL
Buffer
TNFAIP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note
TNFAIP1 antibody can be used for the detection of TNFAIP1 by Western blot at 1 - 2 μ g/mL. Antibody can also be used for immunohistochemistry at 10 μ g/ml.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Homology
Predicted species reactivity based on immunogen sequence: Chicken: (100%)
Manufacturer - Specificity
TNFAIP1 antibody is human, mouse and rat reactive. TNFAIP1 antibody is predicted to not cross-react with other TNFAIP proteins.
Immunogen
TNFAIP1 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human TNFAIP1.

The immunogen is located within the last 50 amino acids of TNFAIP1.
Clonality
Polyclonal
NCBI Official Name
tumor necrosis factor, alpha-induced protein 1 (endothelial)
NCBI Organism
homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.02 mg
Lieferbar: In stock
lieferbar

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