Anti-CD99 Rabbit mAb

ArtNr	PTM-5991
Hersteller	PTM Biolabs
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Lyophilized powder
Applikationen	ICC, IHC-P
Clon	JRMR-10225-3
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	MIC2,MIC2X,MIC2Y
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Applications	IHC-P, ICC/IF
Manufacturer - Category	Uncategorized
Manufacturer - Targets	CD99
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Cancer, Immunology
Product description	CD99 is a 32kDa transmembrane glycoprotein encoded by the MIC2 gene, which participates in many cell functions such as cell adhesion and migration, endocytosis and exocytosis, and intracellular protein transport. CD99 is mainly expressed in bone marrow pre-B cells, neutrophils, monocytes, thymic cortical T lymphocytes, ovarian granulosa cells, ependymal cells of the central nervous system, and supporting testicular cells. CD99 plays a role in the late stage of leukocyte extravasation, helping leukocytes to overcome endothelial basement membrane. Due to selective cleavage, CD99 produces two isoforms with different carboxyl ends: CD99 type I (CD99wt) is a full-length form containing 185 amino acids, while CD99 type II (CD99sh) contains 161 amino acids. Their expression regulation is different, and may have opposite functions in different environments. CD99 is expressed in many types of tumor cells and is used in the differential diagnosis of Ewing's sarcoma.
Purification Method	Protein A purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Recombinant Monoclonal
Background	CD99 is a 32kDa transmembrane glycoprotein encoded by the MIC2 gene, which participates in many cell functions such as cell adhesion and migration, endocytosis and exocytosis, and intracellular protein transport. CD99 is mainly expressed in bone marrow pre-B cells, neutrophils, monocytes, thymic cortical T lymphocytes, ovarian granulosa cells, ependymal cells of the central nervous system, and supporting testicular cells. CD99 plays a role in the late stage of leukocyte extravasation, helping leukocytes to overcome endothelial basement membrane. Due to selective cleavage, CD99 produces two isoforms with different carboxyl ends: CD99 type I (CD99wt) is a full-length form containing 185 amino acids, while CD99 type II (CD99sh) contains 161 amino acids. Their expression regulation is different, and may have opposite functions in different environments. CD99 is expressed in many types of tumor cells and is used in the differential diagnosis of Ewing's sarcoma.
Cellular Localization	Cell membrane, cytoplasm

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Menge: 100 ul

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Lieferung vsl. bis 19.02.2026

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