Vergleich

Anti-DKK3 Mouse mAb

ArtNr PTM-6353
Hersteller PTM Biolabs
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Lyophilized powder
Applikationen WB, ICC, IHC-P
Clon JMMR-2690
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG2b
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Dickkopf-3,hDkk-3,REIC
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Applications
WB, IHC-P, ICC/IF
Manufacturer - Category
Uncategorized
Manufacturer - Targets
DKK3
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Stability
Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area
Signal Transduction, Stem Cells
Product description
Dickkopf-related protein 3(DKK3) is a protein in the Dickkopf family that is encoded by the DKK3 gene in human. DKK3 contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development.
Purification Method
Protein A purified
Formula
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Background
Dickkopf-related protein 3(DKK3) is a protein in the Dickkopf family that is encoded by the DKK3 gene in human. DKK3 contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development.
Cellular Localization
Secreted

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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