Comparison

Anti-DKK3 Mouse mAb

Item no. PTM-6353
Manufacturer PTM Biolabs
Amount 100 ul
Category
Type Antibody Monoclonal
Format Lyophilized powder
Applications WB, ICC, IHC-P
Clone JMMR-2690
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG2b
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Dickkopf-3,hDkk-3,REIC
Shipping Condition Room temperature
Available
Manufacturer - Type
Primary Antibodies
Manufacturer - Applications
WB, IHC-P, ICC/IF
Manufacturer - Category
Uncategorized
Manufacturer - Targets
DKK3
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Stability
Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area
Signal Transduction, Stem Cells
Product description
Dickkopf-related protein 3(DKK3) is a protein in the Dickkopf family that is encoded by the DKK3 gene in human. DKK3 contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development.
Purification Method
Protein A purified
Formula
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Background
Dickkopf-related protein 3(DKK3) is a protein in the Dickkopf family that is encoded by the DKK3 gene in human. DKK3 contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development.
Cellular Localization
Secreted

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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