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Anti-Acetyl-CoA Carboxylase 1 Mouse mAb

Anti-Acetyl-CoA Carboxylase 1 Mouse mAb

ArtNr	PTM-6540
Hersteller	PTM Biolabs
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Lyophilized powder
Applikationen	WB, IHC-P
Clon	JMMR-1662
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a
Konjugat/Tag	Unconjugated
Citations	Xiaoliu Wang, et al. Mycoplasma genitalium membrane lipoprotein induces GAPDH malonylation in urethral epithelial cells to regulate cytokine response. MICROBIAL PATHOGENESIS, 2024. https://www.sciencedirect.com/science/article/pii/S0882401024003395.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ACACA,ACAC,ACC1,ACCA
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	Acetyl-CoA Carboxylase 1
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Cardiovascular Biology, Signal Transduction, Metabolism, Cancer
Product description	Acetyl-CoA carboxylase 1(ACC1) belongs to the biotin containing enzyme family. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. It is the key enzyme in the biosynthesis and oxidation of fatty acids. Phosphorylation by AMPK at Ser79 or by PKA at Ser1200 inhibits the enzymatic activity of ACC. ACC is a potential target of anti-obesity drugs.
Purification Method	Protein A purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Recombinant Monoclonal
Background	Acetyl-CoA carboxylase 1(ACC1) belongs to the biotin containing enzyme family. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. It is the key enzyme in the biosynthesis and oxidation of fatty acids. Phosphorylation by AMPK at Ser79 or by PKA at Ser1200 inhibits the enzymatic activity of ACC. ACC is a potential target of anti-obesity drugs.
Cellular Localization	Cytosol

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Menge: 100 ul

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Lieferung vsl. bis 19.02.2026

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