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Anti-Coronin 1A Antibody

Anti-Coronin 1A Antibody

ArtNr	COR
Hersteller	Aves Labs
Menge	1000 uL
Kategorie	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Chicken
Isotype	IgY
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Coronin-1A, Coronin-like protein A, Clipin-A, Coronin-like protein p57, Tryptophan aspartate-containing coat protein, TACO
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibody
Manufacturer - Category	Cell Markers, Glial and Schwann Cell Markers
Manufacturer - Targets	Coronin 1a
Country of Origin	United States
Storage Conditions	Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.
Molecular Weight	51 kDa
Concentration	100 µg/mL
Buffer	Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (“PBS, " pH 7.2) with sodium azide (0.02%, w/v) added as a preservative.
Quality Control	Quality assurance analysis was performed using immunohistochemistry (at a dilution of 1:2000) using fluorescein-labeled goat anti-chicken IgY (1:500 dilution, Aves Labs Cat.# F-1005) as the secondary reagent.
Description	This affinity-purified antipeptide antibody was generated in chickens against a sequence shared between the mouse (NP_034028) and human (NP_009005) gene products. The antibody was affinity-purified, and its concentration was adjusted to 100 µg/mL. This antibody has been validated with human, mouse and rat tissues.
Manufacturer - Statement	We produce our Anti-Coronin 1a chicken polyclonal primary antibody. It is great in IHC, ICC, WB and is affinity-purified IgY.
Target Description	Human Coronin 1a is a 51, 026 dalton protein (461 amino acids) selectively expressed in cells involved in immune surveillance throughout the body, including activated microglial cells of the CNS. It is a member of the WD40 (tryptophan-aspartate) gene family, which includes the beta subunit of the trimeric G proteins as the prototype. Its function is presumably in membrane structural reorganization accompanying antigen-presentation.
Antibody Registry ID (RRID)	AB_2313539
Clonality	Polyclonal
Dilution Range ICC	1:1000-1:2000
Dilution Range IHC	1:1000-1:2000
Dilution Range Western Blot	1:5000-1:10000
Immunogen	Synthetic peptide
Immunogen Species	Human, Mouse, Rat
Manufacturer - Form	Affinity-Purified IgY
Expiration	12 months from receipt of product
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Production Notes	Chickens were immunized with a synthetic peptide / keyhole limpet hemocyanin (KLH) conjugate. This synthetic peptide corresponded to a sequence shared between the human (NM_007074) and mouse (NM_009898) gene products. After repeated injections, immune eggs were collected, the IgY fractions were purified from the yolks, and then affinity purified using a peptide column. The concentration of the eluate was then adjusted to 100 µg/mL, and the preparation was filter-sterilized.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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COR-datasheet.pdf

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Menge: 1000 uL

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Lieferung vsl. bis 25.09.2025

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