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Anti-Proteolipid Protein (PLP) Antibody

Anti-Proteolipid Protein (PLP) Antibody

ArtNr	PLP
Hersteller	Aves Labs
Menge	1000 uL
Kategorie	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Chicken
Isotype	IgY
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Myelin proteolipid protein, PLP, Lipophilin
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibody
Manufacturer - Category	Cell Markers, Glial and Schwann Cell Markers
Manufacturer - Targets	Proteolipid Protein (PLP)
Country of Origin	United States
Storage Conditions	Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.
Molecular Weight	30 kDa
Concentration	100 µg/mL
Buffer	Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (“PBS, " pH 7.2) with sodium azide (0.02%, w/v) added as a preservative.
Quality Control	Each of the three antibodies were analyzed by immunohistochemistry (at a dilution of 1:2000) using fluorescein-labeled goat anti-chicken IgY (1:500 dilution, Aves Labs Cat.# F-1005) as the secondary reagent.
Description	An antipeptide antibody was generated in chickens against a sequence shared between the mouse (P60202) and human (NP_000524) gene products. Antibodies were affinity-purified and the concentration adjusted to 100 µg/mL. These antibodies have been validated with human, mouse and rat tissues.
Manufacturer - Statement	We produce our Anti-Proteolipid Protein (PLP) chicken polyclonal primary antibody. It is great in IHC, ICC, WB and is affinity-purified IgY.
Target Description	Human Proteolipid Protein (PLP, or lipophilin) is a 29, 946 dalton protein (277 amino acids) found in myelin of the CNS and PNS. Expressed by oligodendrocytes and Schwann cells, PLP stabilizes myelin by preventing lipid bilayer fusion, and aids in its compaction. Different mutations of the human PLP gene product result in two neurological disorders: Pelizaeus-Merzbacher Disease and Spastic Paraplegia Type 2.
Antibody Registry ID (RRID)	AB_2313560
Clonality	Polyclonal
Dilution Range ICC	1:2000-1:5000
Dilution Range IHC	1:2000-1:5000
Dilution Range Western Blot	1:2000-1:5000
Immunogen	Synthetic peptide
Immunogen Species	Human, Mouse, Rat
Manufacturer - Form	Affinity-Purified IgY
Expiration	12 months from receipt of product
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Production Notes	Chickens were immunized with a synthetic peptide-keyhole limpet hemocyanin (KLH) conjugate. This synthetic peptide corresponded to the PLP gene product shared between the mouse (P60202) and human (NP_000524) gene products. After repeated injections into the hens, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity purified using a peptide column, the concentrations of the eluate adjusted to 100 µg/mL, and the preparation filter-sterilized.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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PLP-datasheet.pdf

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Menge: 1000 uL

lieferbar

Lieferung vsl. bis 25.09.2025

Express-Lieferung: 1 Tage sparen

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