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GluR2 Antibody (Phospho-Ser880)

ArtNr OAPC00170
Hersteller AVIVA Systems Biology
Menge 100 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio)
Host Rabbit
Citations Hollmann M, Heinemann S (1994) Cloned glutamate receptors. Annu Rev Neurosci 17:31-108.
Keinänen K, Wisden W, Sommer B, Werner P, Herb A, Verdoorn TA, Sakmann B, Seeburg PH (1990) A family of AMPA-selective glutamate receptors. Science 249:556-560.
Soderling TR, Derkach VA (2000) Postsynaptic protein phosphorylation and LTP. Trends Neurosci 23:75-80.
Matsuda S., Mikawa S., and Hirai H (199) Phosphorylation of serine 880 in GluR2 by protein kinase C prevents it's C-terminus from binding with glutamate receptor interacting protein. J. Neurochem 73, 1765-1768.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GluA2,GluR2,gluR-B,GluR-K2
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
~100kDa
Manufacturer - Application Additional Information
The antibody has been directly tested for reactivity in Western blots in rat tissues. It is anticipated that the antibody will react with chicken, human, mouse, non-human primate and Zebrafish tissues based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
Western blot of rat brain homogenate showing specific immunolabeling of the ~100k GluR2 protein phosphorylated at Ser880 (control). Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (Peptide)but not by the corresponding dephospho-peptide (not shown).
Gene symbol
GluR2
Product format
Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.
Reconstitution and storage
Store at -20C; stable for at least one year.
Protein accession_num
NP_001077280.1
Protein name
Glutamate receptor 2
Clonality
Polyclonal
Purification
Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephospho-peptide affinity columns.
Immunogen
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser880 of rat GluR2.
Homology
Human; Mouse; Rat; Zebrafish
Manufacturer - Specificity
Specific for the ~100k GluR2 protein phosphorylated at Ser880.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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