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BCL11A antibody - C-terminal region (ARP39569_P050)

BCL11A antibody - C-terminal region (ARP39569_P050)

ArtNr	ARP39569_P050
Hersteller	AVIVA Systems Biology
Menge	100ul
Kategorie	Oncology Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Epigenetics Antibodies Western Blot Primary Antibodies By Organ Heart & Blood Cancer
Typ	Antibody Polyclonal
Format	Lyophilized powder
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Porcine, Rabbit (Oryctolagus cuniculus), Fish, Guinea Pig, Bovine, Canine, Equine
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, ZNF856
Similar products	BCL11A
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Gene symbol	BCL11A
Protein name	B-cell lymphoma/leukemia 11A
Protein size	835
Molecular weight	91kDa
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id	53335
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	GMCL1P1. ZBTB24. NCK2. LMO1. NR2E3. NR2E1. NR2F2. NR2F1. NR2F6. HDAC2. HDAC1. CDCA3. YME1L1. CDK6. CDK4. ACTC1. APP. UBC. BCL6. BCL11A. Sumo1. SUMO2. SUMO3. SIRT1. MBD3. MTA2. MTA1. CHD4.
Description of target	BCL11A is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression.
Homology	Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Purification	Affinity Purified
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the C terminal region of human BCL11A
Drywet	Wet Ice

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