Item no. |
ARP39569_P050 |
Manufacturer |
AVIVA Systems Biology
|
Amount |
100ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Lyophilized powder |
Applications |
WB |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Porcine, Rabbit (Oryctolagus cuniculus), Fish, Guinea Pig, Bovine, Canine, Equine |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, ZNF856 |
Similar products |
BCL11A |
Available |
|
Gene symbol |
BCL11A |
Protein name |
B-cell lymphoma/leukemia 11A |
Protein size |
835 |
Molecular weight |
91kDa |
Product format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Gene id |
53335 |
Reconstitution and storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Partner proteins |
GMCL1P1. ZBTB24. NCK2. LMO1. NR2E3. NR2E1. NR2F2. NR2F1. NR2F6. HDAC2. HDAC1. CDCA3. YME1L1. CDK6. CDK4. ACTC1. APP. UBC. BCL6. BCL11A. Sumo1. SUMO2. SUMO3. SIRT1. MBD3. MTA2. MTA1. CHD4. |
Description of target |
BCL11A is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. |
Homology |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
Purification |
Affinity Purified |
Clonality |
Polyclonal |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human BCL11A |
Drywet |
Wet Ice |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.