LCK Antibody - N-terminal region

ArtNr	OAAB17227
Hersteller	AVIVA Systems Biology
Menge	400 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Aging & Neurological Disorders Neural Signaling Protein Aggregation, Clearance & Misfolding Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Mesothelioma Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Autophagy Cardiovascular Research Proliferation Myocardial Infarction Primary Antibodies Astrocytoma By Organ Colorectal Cancer Heart & Blood Cancer Calcium Binding Protein Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, FC, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	LSK,YT16,IMD22,p56lck,pp58lck
Similar products	LCK, Leukocyte C-terminal Src kinase, Lymphocyte cell-specific protein-tyrosine kinase, p56-LCK, Tyrosine-protein kinase Lck, Protein YT16, Proto-oncogene Lck, T cell-specific protein-tyrosine kinase
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	Ig
Shipping Temperature	Wet Ice
Molecular Weight	58001 Da
Manufacturer - Application Additional Information	WB: 1:1000 IHC-P: 1:50~100 IF: 1:10~50 FC: 1:10~50
Gene symbol	LCK
Product format	Liquid. PBS with 0.09% (W/V) sodium azide.
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	LSK, which belongs to the SRC subfamily of Tyr protein kinases, may participate in antigen-induced T-cell activation. It binds to phosphatidylinositol 3'-kinase (PI3K) from T lymphocytes through its SH3 domain and to the tyrosine phosphorylated form of KHDRBS1/p70 through its SH2 domain. LSK is bound to the cytoplasmic domain of either CD4 or CD8. This protein is involved in leukemias by a chromosomal translocation t(1; 7)(p34; q34) which involves LCK and T-cell receptor beta chain (TCRB) genes.
Protein accession_num	NP_001036236.1
Protein name	Tyrosine-protein kinase Lck
Clonality	Polyclonal
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen	This LCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human LCK.
Concentration	Approximately 0.5mg/ml. Actual concentration varies with each lot.

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Menge: 400 ul

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