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LCK Antibody - N-terminal region (OAAB17227)

LCK Antibody - N-terminal region (OAAB17227)

Manufacturer	AVIVA Systems Biology
Category	Oncology Neuroscience Neural Lineage Markers Neural Signaling Protein Aggregation, Clearance & Misfolding Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Astrocytoma By Organ Colorectal Cancer Heart & Blood Cancer Calcium Binding Protein Markers
Type	Antibody Polyclonal
Specific against	Human, Mouse
Isotype	Ig
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, FC, IF, IHC
Amount	400ul
Host	Rabbit
Item no.	OAAB17227
eClass 6.1	32160702
eClass 9.0	32160702
Available
Gene symbol	LCK
Protein name	Tyrosine-protein kinase Lck
Molecular weight	58001 Da
Product format	Liquid. PBS with 0.09% (W/V) sodium azide.
Gene id	3932
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	LSK, which belongs to the SRC subfamily of Tyr protein kinases, may participate in antigen-induced T-cell activation. It binds to phosphatidylinositol 3'-kinase (PI3K) from T lymphocytes through its SH3 domain and to the tyrosine phosphorylated form of KHDRBS1/p70 through its SH2 domain. LSK is bound to the cytoplasmic domain of either CD4 or CD8. This protein is involved in leukemias by a chromosomal translocation t(1; 7)(p34; q34) which involves LCK and T-cell receptor beta chain (TCRB) genes.
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Immunogen	This LCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human LCK.
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400ul

available

Delivery expected until 6/13/2024