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SQSTM1 Antibody (Phospho-Ser351) (OAAB18212)

SQSTM1 Antibody (Phospho-Ser351) (OAAB18212)

ArtNr	OAAB18212
Hersteller	AVIVA Systems Biology
Menge	400 ul
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Signaling Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Cell Biology Cell Status Adenocarcinoma Western Blot Autophagy Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Sequestosome-1, STONE14, Ubiquitin-binding protein p62, Sqstm1, A170, STAP
Similar products	STAP, Sequestosome-1, Ubiquitin-binding protein p62, Sqstm1, A170, STONE14
Lieferbar
Gene symbol	SQSTM1
Molecular weight	48163 Da
Product format	Liquid. PBS with 0.09% (W/V) sodium azide.
Gene id	18412
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Adapter that mediates the interaction between TRAF6 and CYLD.
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Immunogen	This Phospho-Sqstm1(S351) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 346-379 amino acids from the human region of human Phospho-Sqstm1(S351).
Drywet	Wet Ice

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OAAB18212-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 25.09.2025

Express-Lieferung: 9 Tage sparen

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