Comparison

SQSTM1 Antibody (Phospho-Ser351) (OAAB18212)

Item no. OAAB18212
Manufacturer AVIVA Systems Biology
Amount 400 ul
Category
Type Antibody Polyclonal
Format Liquid. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Applications WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Sequestosome-1, STONE14, Ubiquitin-binding protein p62, Sqstm1, A170, STAP
Similar products STAP, Sequestosome-1, Ubiquitin-binding protein p62, Sqstm1, A170, STONE14
Available
Gene symbol
SQSTM1
Molecular weight
48163 Da
Product format
Liquid. PBS with 0.09% (W/V) sodium azide.
Gene id
18412
Reconstitution and storage
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target
Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Adapter that mediates the interaction between TRAF6 and CYLD.
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality
Polyclonal
Immunogen
This Phospho-Sqstm1(S351) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 346-379 amino acids from the human region of human Phospho-Sqstm1(S351).
Drywet
Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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