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PTPN6 Antibody

ArtNr OAAF00647
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Citations Laura A. Maile, Mol. Biol. Cell, Sep 2003; 14: 3519.
Tony Avril, J. Immunol., Dec 2004; 173: 6841 - 6849.
Hong Xu, J. Biol. Chem., Jul 1998; 273: 17987.
Gregory Bix, Blood, Dec 2006; 10: 1182.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias HCP;HCPH;hematopoietic cell phosphatase;hematopoietic cell protein-tyrosine phosphatase;HPTP1C;protein-tyrosine phosphatase 1C;protein-tyrosine phosphatase SHP-1;PTP-1C;SHP1;SHP-1;SHP-1L;SH-PTP1;tyrosine-protein phosphatase non-receptor type 6.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
67 kDa
Manufacturer - Application Additional Information
WB: 1:500~1000; IHC: 1:50~100; ELISA: 1:20000
Gene symbol
PTPN6
Gene Fullname
protein tyrosine phosphatase non-receptor type 6
Product format
Liquid
Reconstitution and storage
-20°C
Description of target
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Protein accession_num
NP_002822.2
Protein name
Tyrosine-protein phosphatase non-receptor type 6
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human SHP-1.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
SHP-1 (Ab-536) antibody detects endogenous levels of total SHP-1 protein.
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

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