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PTPN6 Antibody

PTPN6 Antibody

Item no.	OAAF00647
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Culture Cytokines Adenocarcinoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Astrocytoma By Organ Bladder Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	Laura A. Maile, Mol. Biol. Cell, Sep 2003; 14: 3519. Tony Avril, J. Immunol., Dec 2004; 173: 6841 - 6849. Hong Xu, J. Biol. Chem., Jul 1998; 273: 17987. Gregory Bix, Blood, Dec 2006; 10: 1182.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	HCP;HCPH;hematopoietic cell phosphatase;hematopoietic cell protein-tyrosine phosphatase;HPTP1C;protein-tyrosine phosphatase 1C;protein-tyrosine phosphatase SHP-1;PTP-1C;SHP1;SHP-1;SHP-1L;SH-PTP1;tyrosine-protein phosphatase non-receptor type 6.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	67 kDa
Manufacturer - Application Additional Information	WB: 1:500~1000; IHC: 1:50~100; ELISA: 1:20000
Gene symbol	PTPN6
Gene Fullname	protein tyrosine phosphatase non-receptor type 6
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Protein accession_num	NP_002822.2
Protein name	Tyrosine-protein phosphatase non-receptor type 6
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human SHP-1.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	SHP-1 (Ab-536) antibody detects endogenous levels of total SHP-1 protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/29/2026

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