Vergleich

PTPN1 Antibody

ArtNr OAAF00958
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host Rabbit
Citations Gang Xu, J. Biol. Chem., Dec 2002; 277: 49989 - 49997.
Yinges Yigzaw, J. Biol. Chem., Jan 2003; 278: 284 - 288.
Jinseol Rhee, J. Biol. Chem., Feb 2001; 276: 6640 - 6644.
Fawaz G. Haj, Science, Mar 2002; 295: 1708
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias protein tyrosine phosphatase,placental;protein-tyrosine phosphatase 1B;PTP1B;tyrosine-protein phosphatase non-receptor type 1.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
49 kDa
Manufacturer - Application Additional Information
WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:20000
Gene symbol
PTPN1
Gene Fullname
protein tyrosine phosphatase non-receptor type 1
Product format
Liquid
Reconstitution and storage
-20°C
Description of target
Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
Protein accession_num
NP_002818.1
Protein name
Tyrosine-protein phosphatase non-receptor type 1
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human PTP1B.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
PTP1B (Ab-50) antibody detects endogenous levels of total PTP1B protein.
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

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