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PTPN1 Antibody

PTPN1 Antibody

Item no.	OAAF00958
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Myelofibrosis Mesothelioma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining Stem Cell Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host	Rabbit
Citations	Gang Xu, J. Biol. Chem., Dec 2002; 277: 49989 - 49997. Yinges Yigzaw, J. Biol. Chem., Jan 2003; 278: 284 - 288. Jinseol Rhee, J. Biol. Chem., Feb 2001; 276: 6640 - 6644. Fawaz G. Haj, Science, Mar 2002; 295: 1708
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	protein tyrosine phosphatase,placental;protein-tyrosine phosphatase 1B;PTP1B;tyrosine-protein phosphatase non-receptor type 1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	49 kDa
Manufacturer - Application Additional Information	WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:20000
Gene symbol	PTPN1
Gene Fullname	protein tyrosine phosphatase non-receptor type 1
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
Protein accession_num	NP_002818.1
Protein name	Tyrosine-protein phosphatase non-receptor type 1
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human PTP1B.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	PTP1B (Ab-50) antibody detects endogenous levels of total PTP1B protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/29/2026

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