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USP14 Antibody - N-terminal region

ArtNr OAAB17737
Hersteller AVIVA Systems Biology
Menge 400 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Citations Deshpande K.L., et al. Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases.
Kalnine N., et al. Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Reuter T.Y., et al. Exp. Cell Res. 289:211-221(2003).
Carrascal M., et al. J. Proteome Res. 7:5167-5176(2008).
Koulich E., et al. Mol. Biol. Cell 19:1072-1082(2008).
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias TGT
Similar products TGT, USP14, Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-p
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Category
Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
56 kDa
Manufacturer - Application Additional Information
IF: 1:25
FC: 1:25
WB: 1:1000
Gene symbol
USP14
Product format
Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reconstitution and storage
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target
Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).
Protein accession_num
NP_001032411.1, NP_005142.1
Clonality
Monoclonal
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen
Purified His-tagged USP14 protein was used to produced this monoclonal antibody.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
lieferbar

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