USP14 Antibody - N-terminal region

Item no.	OAAB17737
Manufacturer	AVIVA Systems Biology
Amount	400 ul
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Immunohistochemistry Western Blot Autophagy Cardiovascular Research Atherosclerosis Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Citations	Deshpande K.L., et al. Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases. Kalnine N., et al. Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Reuter T.Y., et al. Exp. Cell Res. 289:211-221(2003). Carrascal M., et al. J. Proteome Res. 7:5167-5176(2008). Koulich E., et al. Mol. Biol. Cell 19:1072-1082(2008).
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	TGT
Similar products	TGT, USP14, Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-p
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	56 kDa
Manufacturer - Application Additional Information	IF: 1:25 FC: 1:25 WB: 1:1000
Gene symbol	USP14
Product format	Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).
Protein accession_num	NP_001032411.1, NP_005142.1
Clonality	Monoclonal
Purification	This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen	Purified His-tagged USP14 protein was used to produced this monoclonal antibody.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/13/2025

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