Vergleich

STAT3 Antibody (OAAB17784)

ArtNr OAAB17784
Hersteller AVIVA Systems Biology
Menge 400 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Applikationen WB
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a kappa
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Signal transducer and activator of transcription 3, Acute-phase response factor, STAT3, APRF
Similar products STAT3, APRF, Signal transducer and activator of transcription 3, Acute-phase response factor
Lieferbar
Gene symbol
STAT3
Molecular weight
88 kDa
Product format
Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Gene id
6774
Reconstitution and storage
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Homology
Mouse; Pig; Rat
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Clonality
Monoclonal
Immunogen
This STAT3 antibody is generated from a mouse immunized with a recombinant protein from human.
Drywet
Wet Ice

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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