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STAT3 Antibody

STAT3 Antibody

Item no.	OAAB17784
Manufacturer	AVIVA Systems Biology
Amount	400 ul
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Neural Transcription Factors Neural Signaling Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Culture Cytokines Adenocarcinoma Western Blot Primary Antibodies Astrocytoma Calcium Binding Protein Markers Interneuron Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	WB
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Pig (Porcine, Sus scrofa domesticus)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Akira S., et al.Cell 77:63-71(1994). Della Pietra L., et al.Gene 213:119-124(1998). Ota T., et al.Nat. Genet. 36:40-45(2004). Della Pietra L., et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases. Zhang X., et al.Science 267:1990-1994(1995).
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	APRF,HIES,ADMIO,ADMIO1
Similar products	STAT3, APRF, Signal transducer and activator of transcription 3, Acute-phase response factor
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	IgG2a, kappa
Shipping Temperature	Wet Ice
Molecular Weight	88 kDa
Manufacturer - Application Additional Information	WB: 1:1000
Gene symbol	STAT3
Product format	Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Clonality	Monoclonal
Purification	This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen	This STAT3 antibody is generated from a mouse immunized with a recombinant protein from human.
Homology	Mouse; Pig; Rat

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/27/2025

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