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RUNX2 Antibody - N-terminal region

ArtNr OAAB18599
Hersteller AVIVA Systems Biology
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen IHC
Specific against Human (Homo sapiens)
Host Rabbit
Citations Rich, J.T., Biochem. Biophys. Res. Commun. 372 (1), 230-235 (2008)
Ermakov, S., Ann. Hum. Genet. 72 (PT 4), 510-518 (2008)
Endo, T., J. Clin. Endocrinol. Metab. 93 (6), 2409-2412 (2008)
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CCD,AML3,CCD1,CLCD,OSF2,CBFA1,OSF-2,PEA2aA,PEBP2aA,CBF-alpha-1
Similar products Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit alpha-1, Oncogene AML-3, CBF-alpha-1, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEBP2-alpha A, PEA2-alpha A, SL3-3 enhancer factor 1 alpha A
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
Wet Ice
Molecular Weight
57 kDa
Manufacturer - Application Additional Information
IHC-P: 1:10~50
Gene symbol
RUNX2
Product format
Liquid. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reconstitution and storage
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target
Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
Protein accession_num
NP_001015051.3, NP_001019801.3
Clonality
Polyclonal
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RUNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human RUNX2.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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