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RUNX2 Antibody - N-terminal region

RUNX2 Antibody - N-terminal region

Item no.	OAAB18599
Manufacturer	AVIVA Systems Biology
Amount	400 ul
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Epigenetics Neural Development Antibodies By Cell Type Hematology Leukemia Immunohistochemistry Western Blot Primary Antibodies By Organ Bladder Cancer Heart & Blood Cancer Neurodegeneration Markers Neuronal Cell Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Citations	Rich, J.T., Biochem. Biophys. Res. Commun. 372 (1), 230-235 (2008) Ermakov, S., Ann. Hum. Genet. 72 (PT 4), 510-518 (2008) Endo, T., J. Clin. Endocrinol. Metab. 93 (6), 2409-2412 (2008)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CCD,AML3,CCD1,CLCD,OSF2,CBFA1,OSF-2,PEA2aA,PEBP2aA,CBF-alpha-1
Similar products	Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit alpha-1, Oncogene AML-3, CBF-alpha-1, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEBP2-alpha A, PEA2-alpha A, SL3-3 enhancer factor 1 alpha A
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Wet Ice
Molecular Weight	57 kDa
Manufacturer - Application Additional Information	IHC-P: 1:10~50
Gene symbol	RUNX2
Product format	Liquid. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
Protein accession_num	NP_001015051.3, NP_001019801.3
Clonality	Polyclonal
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen	This RUNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human RUNX2.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 2/12/2026

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