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ADAM15 Antibody - Biotin Conjugated

ADAM15 Antibody - Biotin Conjugated

ArtNr	OACA00780
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Food Safety Allergenes Neuroscience Neural Signaling Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Biotin
Purity	Caprylic Acid Ammonium Sulfate Precipitation purified
Citations	[1] Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence.'Kraetzschmar J., Lum L., Blobel C.P.J. Biol. Chem. 271:4593-4596(1996) [2] Expression of a disintegrin-like protein in cultured human vascular cells and in vivo.'Herren B., Raines E.W., Ross R.FASEB J. 11:173-180(1997) [3] ADAM-15 inhibits wound healing in human intestinal epithelial cell monolayers.'Charrier L., Yan Y., Driss A., Laboisse C.L., Sitaraman S.V., Merlin D.Am. J. Physiol. 288:G346-G353(2005)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	a disintegrin and metalloproteinase domain 15 (metargidin);disintegrin and metalloproteinase domain-containing protein 15;MDC15;MDC-15;metalloprotease RGD disintegrin protein;metalloproteinase-like,disintegrin-like,and cysteine-rich protein 15;Metargidin.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	ADAM15
Gene Fullname	ADAM metallopeptidase domain 15
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.
Nucleotide accession_num	NM_001261464.1; NM_001261465.1; NM_001261466.1; NM_003815.4; NM_207191.2; NM_207194.2
Protein accession_num	NP_001248393.1; NP_001248394.1; NP_001248395.1; NP_003806.3; NP_997074.1; NP_997077.1
Protein name	Disintegrin and metalloproteinase domain-containing protein 15
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Disintegrin and metalloproteinase domain-containing protein 15 protein (207-452AA)
Storage Buffer	Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

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Menge: 100 ug

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Lieferung vsl. bis 25.12.2025

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