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ADAM15 Antibody - Biotin Conjugated

ADAM15 Antibody - Biotin Conjugated

Item no.	OACA00780
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Food Safety Allergenes Neuroscience Neural Signaling Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Biotin
Purity	Caprylic Acid Ammonium Sulfate Precipitation purified
Citations	[1] Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence.'Kraetzschmar J., Lum L., Blobel C.P.J. Biol. Chem. 271:4593-4596(1996) [2] Expression of a disintegrin-like protein in cultured human vascular cells and in vivo.'Herren B., Raines E.W., Ross R.FASEB J. 11:173-180(1997) [3] ADAM-15 inhibits wound healing in human intestinal epithelial cell monolayers.'Charrier L., Yan Y., Driss A., Laboisse C.L., Sitaraman S.V., Merlin D.Am. J. Physiol. 288:G346-G353(2005)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	a disintegrin and metalloproteinase domain 15 (metargidin);disintegrin and metalloproteinase domain-containing protein 15;MDC15;MDC-15;metalloprotease RGD disintegrin protein;metalloproteinase-like,disintegrin-like,and cysteine-rich protein 15;Metargidin.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	ADAM15
Gene Fullname	ADAM metallopeptidase domain 15
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.
Nucleotide accession_num	NM_001261464.1; NM_001261465.1; NM_001261466.1; NM_003815.4; NM_207191.2; NM_207194.2
Protein accession_num	NP_001248393.1; NP_001248394.1; NP_001248395.1; NP_003806.3; NP_997074.1; NP_997077.1
Protein name	Disintegrin and metalloproteinase domain-containing protein 15
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Disintegrin and metalloproteinase domain-containing protein 15 protein (207-452AA)
Storage Buffer	Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/25/2025

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