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PLA2G2A Antibody - FITC Conjugated

ArtNr OACA01742
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag FITC
Purity Caprylic Acid Ammonium Sulfate Precipitation purified
Citations [1] Cloning and recombinant expression of phospholipase A2 present in rheumatoid arthritic synovial fluid.'Seilhamer J.J., Pruzanski W., Vadas P., Plant S., Miller J.A., Kloss J., Johnson L.K.J. Biol. Chem. 264:5335-5338(1989)
[2] Structure and properties of a human non-pancreatic phospholipase A2.'Kramer R.M., Hession C., Johansen B., Hayes G., McGray P., Chow E.P., Tizard R., Pepinsky R.B.J. Biol. Chem. 264:5768-5775(1989)
[3] Structure and properties of a secretable phospholipase A2 from human platelets.'Kramer R.M., Johansen B., Hession C., Pepinsky R.B.Adv. Exp. Med. Biol. 275:35-53(1990)
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GIIC sPLA2;group IIA phospholipase A2;MOM1;non-pancreatic secretory phospholipase A2;NPS-PLA2;phosphatidylcholine 2-acylhydrolase 2A;phospholipase A2,group IIA (platelets,synovial fluid);phospholipase A2,membrane associated;PLA2;PLA2B;PLA2L;PLA2S;PLAS1;sPLA2.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Gene symbol
PLA2G2A
Gene Fullname
phospholipase A2 group IIA
Product format
Liquid
Reconstitution and storage
-20°C or -80°C
Description of target
Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).
Protein name
Phospholipase A2, membrane associated
Clonality
Polyclonal
Purification
Protein G Purified
Immunogen
Recombinant Human Phospholipase A2, membrane associated protein (21-144AA)
Storage Buffer
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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