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PLA2G2A Antibody - FITC Conjugated

PLA2G2A Antibody - FITC Conjugated

Item no.	OACA01742
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Neural Adhesion Molecules Antibodies By Cell Type Carcinoma Cell Biology Cell Movement Cell Adhesion Western Blot ELISA Cardiovascular Research Thrombosis & Hemostasis Enzymes Fatty Acid Catabolism Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	FITC
Purity	Caprylic Acid Ammonium Sulfate Precipitation purified
Citations	[1] Cloning and recombinant expression of phospholipase A2 present in rheumatoid arthritic synovial fluid.'Seilhamer J.J., Pruzanski W., Vadas P., Plant S., Miller J.A., Kloss J., Johnson L.K.J. Biol. Chem. 264:5335-5338(1989) [2] Structure and properties of a human non-pancreatic phospholipase A2.'Kramer R.M., Hession C., Johansen B., Hayes G., McGray P., Chow E.P., Tizard R., Pepinsky R.B.J. Biol. Chem. 264:5768-5775(1989) [3] Structure and properties of a secretable phospholipase A2 from human platelets.'Kramer R.M., Johansen B., Hession C., Pepinsky R.B.Adv. Exp. Med. Biol. 275:35-53(1990)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GIIC sPLA2;group IIA phospholipase A2;MOM1;non-pancreatic secretory phospholipase A2;NPS-PLA2;phosphatidylcholine 2-acylhydrolase 2A;phospholipase A2,group IIA (platelets,synovial fluid);phospholipase A2,membrane associated;PLA2;PLA2B;PLA2L;PLA2S;PLAS1;sPLA2.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	PLA2G2A
Gene Fullname	phospholipase A2 group IIA
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).
Protein name	Phospholipase A2, membrane associated
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Phospholipase A2, membrane associated protein (21-144AA)
Storage Buffer	Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/25/2025

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