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Anti-BCMA (human) (Vicky-1) Antibody

ArtNr OAED00318
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Applikationen WB, FC, ICC, ELISA, FA
Clon Vicky-1
Specific against Human (Homo sapiens)
Host Rat
Isotype IgG1
Purity Protein G-affinity purified.<br/>
Citations Autoantibody-producing RP105(-) B cells, from patients with systemic lupus erythematosus, showed more preferential expression of BCMA compared with BAFF-R than normal subjects: S. Koarada, et al.; Rheumatology (Oxford) 49, 662 (2010), Abstract; Full Text
The rGel/BLyS fusion toxin inhibits diffuse large B-cell lymphoma growth in vitro and in vivo: M.A. Lyu, et al.; Neoplasia 12, 366 (2010), Abstract;
TACI regulates IgA production by APRIL in collaboration with HSPG: D. Sakurai, et al.; Blood 109, 2961 (2007), Abstract;
BAFF AND APRIL: a tutorial on B cell survival: F. Mackay, et al.; Annu. Rev. Immunol. 21, 231 (2003), Abstract;
BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population: J.S. Thompson, et al.; J. Exp. Med. 192, 129 (2000), Abstract; Full Text
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias B cell maturation antigen;B-cell maturation factor;B-cell maturation protein;BCM;BCMA;CD269;TNFRSF13A;tumor necrosis factor receptor superfamily member 17.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Category
Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Manufacturer - Application Additional Information
ELISA
Flow Cytometry
Immunocytochemistry
Functional Application (blocks binding of BAFF to human BCMA)
Optimal conditions must be determined individually for each application.
Gene symbol
TNFRSF17
Gene Fullname
TNF receptor superfamily member 17
Reconstitution and storage
Long Term Storage : -20C
Short Term Storage : -20C
Handling : Avoid freeze/thaw cycles.
Stable for at least 1 year after receipt when stored as recommended.
Description of target
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Protein name
Tumor necrosis factor receptor superfamily member 17
Clonality
Monoclonal
Immunogen
Recombinant human BCMA extracellular domain (aa 2-54) (Prod. No. ALX-522-026).
Manufacturer - Specificity
Recognizes human BCMA. Does not cross-react with mouse BCMA.
Formulation
Liquid. In PBS containing 0.02% sodium azide.
Concentration
1mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

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