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CHIMAERIC Human IgE ANTI NP Antibody

ArtNr OASA00004
Hersteller AVIVA Systems Biology
Menge 2 ml
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen ELISA, FA
Clon JW8/1
Specific against Human (Homo sapiens)
Host Human
Isotype IgE
Citations 1. Neuberger, M. S. et al. (1984) Recombinant antibodies possessing novel effector functions. Nature 312: 604-608.
2. Neuberger, M. S. et al. (1985) Making novel antibodies by expressing transfected immunoglobulin genes. TIBS 347-349.
3. Neuberger, M. S. et al. (1985) A hapten-specific chimaeric IgE antibody with Human physiological effector function. Naure 314: 268-270.
4. Neuberger, M. S. et al. (1986) Construction of novel antibodies by use of DNA transfection: design of plasmid vectors. Phil. Trans. R. Soc. Lond. A317: 425-432.
5. Sayers, I. et al. (2004) The importance of Lys-352 of human immunoglobulin E in FcepsilonRII/CD23 recognition. J Biol Chem. 279: 35320-5.
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias N/A
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Category
Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Manufacturer - Application Additional Information
ELISA: 1/20 - 1/100FN: This product contains sodium azide, removal by dialysis is recommended prior to use in functional assays.
Product format
Liquid. None present
Reconstitution and storage
-20°C
Description of target
CHIMAERIC HUMAN IgE ANTI NP
Protein name
Ig epsilon chain C region
Clonality
Monoclonal
Purification
Tissue Culture Supernatant containing 0.2M Tris/HCl pH7.4 and 5-10% foetal calf serum
Immunogen
Hapten, 4-hydroxy-3-nitrophenylacetyl (NP).
Homology
Human
Manufacturer - Specificity
The immunoglobulin heavy chain has been produced by the linking of the antigen-binding, variable region genes of a mouse hybridoma to human constant region genes by in vitro DNA recombination procedures. The resulting chimeric antibody is subsequently expressed by the myeloma cell-line J558L after transfection. (The J558L cell-line self secretes a lambda light chain but no heavy chain). Thus a chimeric human IgE antibody specific for NP has been produced.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 2 ml
Lieferbar: In stock
lieferbar

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